Leaky Gut Syndrome Treatment

What is Leaky Gut Syndrome?

Leaky Gut Syndrome Treatment : The small intestine is about 8 meters long. As our intestines have a curved structure (villi) inside, they have a very large absorption surface area. The average internal absorption surface area of our intestines is 16,000-18,000 m2 on average. This area is as big as a large football stadium. The villi also incorporate microvillus structures with a curved absorption surface to increase the surface area. Microvilli are lined with a single row of endothelial cells. These cells are tightly interlocked. Those tight junctions are called “Tight Junctions (zonula occludens)”. The protein “ZONULIN” plays an essential role in establishing and maintaining a tight junction. The digested nutrients are absorbed by these cells and then pass into the bloodstream. Our intestines are selectively permeable. This particular feature of our intestines prevents harmful substances, microbes, incompletely digested macromolecules from passing through the intestines into the bloodstream. The surface of this intestinal absorption layer, which is covered with mucosa, is covered with a gelatinous secretion called “MUCUS”, which is produced by the endothelium forming the mucosa. This mucus prevents direct contact of intestinal contents (food, digestive secretions) with the mucosa. Thus, it is protected from external factors. The flora of the region is a must for the formation of MUCUS. In the absence of mucus, the endothelium of the mucosa is damaged and as a result, the selective permeability of the intestine is impaired, resulting in the condition called “LEAKY GUT SYNDROME”. As a consequence of leaky gut syndrome, our defense system is alarmed by the passage of substances that should not pass through the intestines into the bloodstream and tries to destroy them. And this starts the allergic process. While attempting to destroy the pathogens that pass into the bloodstream, our defense system gets out of control after a while and begins to perceive its own tissues as foreign (harmful) and attacks its own tissues as well. This is what is called AUTOIMMUNITY and the resulting diseases are called AUTOIMMUN DISEASES (Arthritis, Vasculitis, Gout, Psoriasis, Eczema, Vitiligo, Hashimoto’s Disease, etc.).

WHAT IS LEAKY GUT SYNDROME?

Leaky Gut Syndrome is a condition that occurs with the loss of the selective permeability of the intestine due to the disruption of mucus production after flora damage and the consequent damage to the mucosa.

WHAT IS FECAL ZONULIN TEST?

The repair activities subsequent to the impairment of the selective permeability of the intestine require the use of much larger amounts of the protein ZONULIN than normal. This increases the amount of the protein Zonulin excreted in the feces. We indirectly get an idea of whether the selective permeability of the intestines has been damaged by measuring ZONULIN in the feces.

WHAT CHANGES OCCUR FOLLOWING LEAKY GUT SYNDROME?

• With flora damage and subsequent formation of the leaky gut syndrome, the most dramatic change is a IRREVERSIBLE reduction in intestinal absorptive surface area depending on the severity of inflammation. Treatments can only preserve the existing reserve or reduce the rate of loss.
• As the intestinal contents that should not pass into the bloodstream also pass into the bloodstream, our defense system fights to destroy them. At some stage, this fight becomes misdirected and starts to attack the body’s own tissues. This picture is called “AUTOIMMUNITY”. The onset of one of the autoimmune diseases (rheumatism, fibromyalgia, GUT, vitiligo, psoriasis, etc.) triggers the development of other autoimmune diseases.
• This results in nutritional disorders,
• and developmental disorders, as well.
• This picture can lead to the onset of many psychiatric illnesses, especially depression.
• There may occur defecating disorders.
• Irritable bowel disorders may develop (IBS, spastic colitis).
• Inflammatory bowel diseases may be triggered (Crohn’s disease, ulcerative colitis).
• Lactose and gluten enteropathy may develop.
• And there may also appear food allergies to an increasing number of foods.

What are the Symptoms of Leaky Gut Syndrome?

Leaky Gut Syndrome refers to a condition in which the intestinal wall becomes more permeable than normal. This relies on the theory that the harmful bacteria, toxins and food particles that leak from the intestines into the bloodstream may cause a range of health problems in the body.

Nonetheless, leaky gut syndrome still remains a diagnosis that is not well accepted in medical circles, with symptoms that are often similar to those of other digestive disorders. Hence, the following are among some of the common symptoms associated with intestinal permeability:

Digestive Problems: Diarrhea, constipation and bloating are among the most prominent symptoms of leaky gut syndrome.

Food Sensitivity: Sensitivity to particular foods is associated with intestinal permeability.

Aches and Pains: Both joint pain and muscle pain may be triggered by an inflammatory response that can be caused by harmful bacteria and toxins leaking from the intestines into the bloodstream.

Fatigue: Chronic fatigue and anergia may be associated with leaky gut syndrome.

Skin Problems: Acne, eczema or other skin conditions may be caused by problems in the intestines.

Mood Disorders: Depression, anxiety and other mood disorders have been linked to gut problems, with research supporting the relationship between gut health and brain health.

Autoimmune Diseases: The leaky gut syndrome is thought to predispose to the development of autoimmune diseases.

Nutritional Deficiencies: Nutritional deficiencies, e.g. iron deficiency anemia or vitamin B12 deficiency, may be associated with intestinal permeability.

WHAT IS FLORA?

Certain parts of the human body are inhabited by microorganisms which peacefully live with us, do not harm us, contribute to the vital functions of the region in which they live, cause health problems when not present, whose functions cannot be compensated in any other way, which constantly renew themselves, whose diversity increases under favorable living conditions, and whose number and biodiversity decrease in some unfavorable conditions. Their generic name is FLORA.

HOW MANY TYPES OF FLORA BACTERIA HAVE BEEN IDENTIFIED IN THE DIGESTIVE SYSTEM?

The number of flora bacteria identified in the human digestive tract to date is 1054.

HOW MANY TYPES OF FLORA BACTERIA DO HUMANS HARBOR IN THE ENTIRE DIGESTIVE SYSTEM?

The most important factor in this is the environmental conditions.  Whereas the diversity of flora in those living in large metropolitan areas is as low as 50-60, this figure tends to increase in rural areas. This figure is around 100 to 110 on average in Turkey.

WHAT IS A FLORA TRANSPLANT?

Flora transplantation is the process consisting of collecting flora samples from at least one healthy FLORA DONOR under general anesthesia through endoscopy and colonoscopy from approximately 30 different anatomical regions of the digestive system, with each region being washed with serums suitable for its own characteristics and aspirated back, subjecting these samples to some series of specific procedures, and then transplanting them endoscopically and colonoscopically to the equivalent anatomical regions of the patient under general anesthesia.

IS FLORA TRANSPLANT A PERMANENT TREATMENT?

Yes, it is. If the remaining intestinal tissue accepts the transplanted flora, the treatment will have a lifelong effect.

HOW DO WE BENEFIT FROM A LARGE, RICH AND QUALITY FLORA DIVERSITY?

This brings you a healthy, high quality, productive, happy and long life.

WHY DOES FLORA DIVERSITY MATTER SO MUCH?

We can think of the flora as a staff specialized in its own field and our digestive system as a factory. The higher the number of qualified personnel in the factory, the higher the quality of the product would be. Each and every member of our digestive system has thousands of specific functions. Flora has a vital role in the fulfilment of these functions.

Please contact us to get more detailed information about endoscopic treatments and flora transplantation for obesity. You can reach us via E-mail or Whatsapp.